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T E Cawston Selected Research

type 2 alpha 1 Collagenopathy

4/2014A computer simulation approach to assessing therapeutic intervention points for the prevention of cytokine-induced cartilage breakdown.
8/2002Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines.
9/2001Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways.
7/2001Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown.
9/2000Retinoic acid combines with interleukin-1 to promote the degradation of collagen from bovine nasal cartilage: matrix metalloproteinases-1 and -13 are involved in cartilage collagen breakdown.

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T E Cawston Research Topics

Disease

5type 2 alpha 1 Collagenopathy
04/2014 - 09/2000
5Inflammation (Inflammations)
12/2007 - 10/2001
3Juvenile Arthritis (Juvenile Idiopathic Arthritis)
12/2006 - 11/2005
3Arthritis (Polyarthritis)
10/2006 - 07/2001
3Necrosis
02/2006 - 08/2002
2Joint Diseases (Joint Disease)
10/2006 - 08/2002
2Rheumatoid Arthritis
03/2004 - 10/2001
1Gingival Overgrowth
12/2007
1Bronchiolitis
12/2005
1Pathologic Processes
03/2004
1Spondylarthropathies
03/2004
1Psoriasis (Pustulosis Palmaris et Plantaris)
03/2004
1Psoriatic Arthritis
03/2004
1Hyperplasia
12/2003
1Systemic Scleroderma (Systemic Sclerosis)
09/2001
1Fibrosis (Cirrhosis)
09/2001
1Diffuse Scleroderma (Progressive Systemic Sclerosis)
09/2001

Drug/Important Bio-Agent (IBA)

5Oncostatin MIBA
04/2014 - 07/2001
5Interleukin-1 (Interleukin 1)IBA
04/2014 - 09/2000
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2006 - 08/2002
5Matrix Metalloproteinases (MMPs)IBA
10/2006 - 09/2001
4Collagenases (Collagenase)FDA Link
04/2014 - 07/2001
4CollagenIBA
12/2007 - 09/2000
4Tissue Inhibitor of Metalloproteinase-1IBA
12/2007 - 09/2001
3Interleukin-6 (Interleukin 6)IBA
12/2006 - 07/2001
3Tissue Inhibitor of MetalloproteinasesIBA
11/2005 - 09/2001
3Metalloproteases (Metalloproteinases)IBA
09/2001 - 09/2000
2Proteins (Proteins, Gene)FDA Link
04/2014 - 04/2006
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
03/2004 - 10/2001
2CytokinesIBA
08/2002 - 07/2001
1Conditioned Culture MediaIBA
12/2007
1Cyclosporine (Ciclosporin)FDA LinkGeneric
12/2007
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
12/2006
1C-Reactive ProteinIBA
12/2006
1procollagenaseIBA
10/2006
1proteinase InIBA
10/2006
1Matrix Metalloproteinase 10 (Stromelysin 2)IBA
10/2006
1GelatinasesIBA
04/2006
1ADAMTS4 ProteinIBA
11/2005
1Transforming Growth Factor beta1 (TGF beta 1)IBA
11/2005
1aggrecanaseIBA
11/2005
1Interleukin-4 (Interleukin 4)IBA
11/2005
1EnzymesIBA
03/2004
1ImmunosorbentsIBA
03/2004
1Interleukin-17 (Interleukin 17)IBA
08/2002
1Matrix Metalloproteinase 3 (Stromelysin 1)IBA
10/2001
1Serine (L-Serine)FDA Link
09/2001
1Tissue Inhibitor of Metalloproteinase-2IBA
09/2001
1collagenase 1IBA
09/2001
1Serine Proteases (Serine Protease)IBA
09/2001
1Interleukin-1alpha (Interleukin 1 alpha)IBA
07/2001
1Glycoproteins (Glycoprotein)IBA
07/2001
1batimastat (BB 94)IBA
09/2000
1Tretinoin (Retinoic Acid)FDA LinkGeneric
09/2000

Therapy/Procedure

1Lung Transplantation
12/2005